This, too, is a necrosisof liver of pregnancy homocystinuria
acute fatty liver of pregnancy diagnosis, drug induced fatty liver, epidemiology, replacement therapy, dress up fatty , plump wife , queen fat bottom girls , homocystinuria, fat girls pics , miss plump , women's & children's health center, st. john’s mercy medical center, child care, The diagnosis of acute fatty liver of pregnancy is usually made upon liver biopsy. The biopsy shows an intense infiltration of all the hepatocytes by fat with a marked disruption of the hepatic necrosisof liver of pregnancy architecture. The liver transaminase will be markedly elevated. The alkaline phosphatase will necrosisof liver of pregnancy be slightly elevated. The bilirubin is significantly elevated. It has been recognised as of late that the rapid delivery of the baby will improve the maternal mortality. It has been this understanding which has lead to the improvement in the survival rates from such a condition. There is one case in the literature necrosisof liver of pregnancy where, despite the delivery of the baby, it was felt that the disease process had not been reversed and the patient underwent successful liver transplant.
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This, too, is a condition of unknown cause. It is an extremely rare condition affecting less than 1 homocystinuria in 10,000 patients. The symptoms are that of a rather sudden onset in the last four weeks of pregnancy of rapidly deepening jaundice, somnolence, and in short order, coma, bleeding dyathosis, and hepatorenal failure. The usual time course from onset of symptoms to hepatorenal failure is approximately 2 weeks. The maternal mortality rate homocystinuria from acute fatty liver of pregnancy approaches 30%. Some similarities homocystinuria to this condition with Reye's syndrome have been suggested. However, there is enough variation in the symptoms and the pathology that such an association is suspect.
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