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An elevation of the liver dependent clotting factors such as fibrinogen. In addition, there are clinical information elevations in the transport proteins produced in the liver such as ceruloplasmin , transferrin , and sex steroid binding globulin . The alkaline phosphatase will be elevated 2-4 times normal. Of note clinical information is the fact that the transaminase levels should remain normal during pregnancy. This has tremendous importance clinical information when evaluating the possibility of liver disease in pregnancy. In addition, the bilirubin should stay normal. However, there are also certain liver conditions that may cause complications in pregnancy. These include: Hepatitis The most common liver disease encountered during pregnancy is that of hepatitis. This is no different than in the non-pregnant individual. In some areas around the world such as India, it remains the most common cause of maternal death during pregnancy.
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