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serum transaminase activity) and low levels postpartum of platelets (cell fragments in blood needed for clotting). The liver is infiltrated with fat. If untreated, AFLP can cause complete liver failure, bleeding (because of impaired postpartum blood clotting) and death of the mother and child. AFLP is treated by delivering the baby as soon as possible. Early diagnosis of AFLP and prompt delivery dramatically improve the outcome and the once-bleak outlook. Women with AFLP generally improve soon after delivery, unless the liver damage postpartum is severe. As a general rule, AFLP does not usually recur during a subsequent pregnancy. However, AFLP has been found associated in some cases with an abnormality of fatty-acid metabolism. This abnormality is a deficiency of the enzyme long-chain-3-hydroxyacyl-CoA dehydrogenease (LCHAD).
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