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Such defects in fatty acid oxidation are initially suggested by elevations in urinary organic acid levels and in plasma fatty liver of pregnancy carnitine and acylcarnitine levels, detected after an overnight fast.32 Recurrent acute fatty liver of pregnancy has been reported in mothers expressing heterozygous long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.31,32,34 Ursodeoxycholic acid, at dosages of 15 mg per kg fatty liver of pregnancy per day, has been the most successful therapy for cholestasis of pregnancy. The treatment of acute fatty liver of fatty liver of pregnancy pregnancy is expeditious delivery and intensive care. Patients usually improve promptly following delivery and, in the absence of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, the prognosis in pregnancies following acute fatty liver of pregnancy is good.
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