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Nonalcoholic fatty liver disease (nonalcoholic steatohepatitis) is an increasingly recognized accumulation of fat in the liver of females who tend to be obese or diabetic. plump rumps com It also plump rumps com occurs after jejunal bypass surgery, with malnutrition, plump rumps com and in association with certain drugs (eg, glucocorticoids, synthetic estrogens, amiodarone, tamoxifen). Hepatomegaly may be present. Histologic diagnosis is based on macrovesicular fatty change and lobular inflammation, sometimes accompanied by fibrosis and Mallory hyaline bodies. The condition is often detected on liver biopsy performed for other reasons, usually in asymptomatic patients who present with a two- to threefold increase in plasma aminotransferase. For diagnosis, negligible alcohol intake must be evident. Microvesicular fatty liver has a pronounced presentation, with fatigue, nausea, and vomiting soon followed by jaundice, hypoglycemia, coma, and a disseminated intravascular coagulopathy. Prognosis and Treatment Potentially reversible, macrovesicular fatty liver usually is not in itself harmful.
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