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cystic fibrosis, bsn, prenatal, alcohol related fatty liver, fatty acids definition , plump amateur , cochrane library, fresno, fat girls porn , kidneys, midwifery, fat ass white girls , golden plump , Microscopically, the general architecture can be normal. Triglyceride accumulations appear as large droplets that coalesce and displace the cell omega minus three fatty acids nucleus to the periphery. In the typical example, alcoholic fatty liver, hepatocytes are filled with fat vacuoles omega minus three fatty acids that displace the nuclei to the periphery of the cell, appearing like a large fat cell (see the discussion of fatty liver under Pathology in Ch. 40). In microvesicular fatty liver, small droplets collect in the endoplasmic reticulum and in secondary lysosomes that do not fuse. Hepatocytes exhibit a foamy cytoplasm and a central omega minus three fatty acids nucleus. With hepatotoxins primarily affecting protein synthesis or with protein malnutrition, the lipid tends to collect in zone 1 (periportal). Microvesicular fat tends to collect in zone 3 (central). Symptoms, Signs, and Diagnosis Macrovesicular fatty liver most often is discovered on physical examination as nontender, smooth, diffuse hepatomegaly in an alcoholic, obese, or diabetic patient.
Toxic inhibition of protein synthesis can lead to a fatty liver through inhibition of mRNA synthesis or translation. In microvesicular fatty liver, small droplets of triglyceride plus FFA, cholesterol, and phospholipid collect in subcellular fat ass white girls organelles. The basic defect is unknown, even though pathologic and clinical features from diverse causes are somewhat similar. The biochemical basis may be a disturbance in the mitochondrial-oxidative pathway, depressing FFA oxidation and impairing apolipoprotein synthesis for VLDL assembly. Fatty liver may result from the accumulation of other neutral lipids. fat ass white girls Fat and cholesterol (seen as rhomboid birefringent crystals under polarizing microscopy) are present in Wolman's disease and cholesterol ester storage disease. The fat vacuolization is small to medium. In Niemann-Pick disease, the phospholipid sphingomyelin accumulates in hepatocytes and Kupffer cells. Cells appear foamy. Pathology When lipid deposition is marked, the liver tends to be grossly enlarged, smooth, and pale.
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