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studiesElevations in serum ferritin, iron, and/or decreased transferrin saturation may occur plump milf in patients with NASH.Although iron overload occurs in a small proportion of patients with NASH, these patients have more severe disease. An iron index score may be ordered on a liver biopsy specimen to evaluate plump milf for phlebotomy. Hemochromatosis gene testing plump milf is recommended when the ferritin is significantly elevated.Viral serological markers: Before the diagnosis of NASH can be made, viral markers should be tested and viral infection excluded.Autoimmune markers, such as antinuclear antibody (ANA) and anti–smooth muscle antibody (ASMA), are often slightly elevated in NASH. However, in the appropriate clinical setting, serum protein electrophoresis (SPEP) and anti–liver-kidney antibody may lead to a diagnosis of autoimmune liver disease.Imaging Studies: UltrasoundThe liver is hyperechogenic or bright.Steatosis is detected only when substantial (30% or more) fatty change is present.Computed
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